IL1RN Polymorphism and cagA-Positive Helicobacter pylori Strains Increase the Risk of Duodenal Ulcer in Children
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori infection, cagA status, and duodenal ulcer disease in children.
14 samples from noninoculated guinea pig brains as negative controls. All samples were assayed in a blinded fashion. Detection of the Borrelia and IC amplification products was performed using the DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) time-resolved fluorescence hybridization assay (Perkin-Elmer Wallac, Gaithersburg, MD), as described elsewhere [7]. Probe sequences were as ...
متن کاملEPIYA motif patterns among Cuban Helicobacter pylori CagA positive strains.
INTRODUCTION It is known that polymorphisms in C-terminal region of CagA influence gastric disease development on Helicobacter pylori infection. Additionally, the geographic distribution of these polymorphisms has been associated with the appearance of more severe gastroduodenal pathologies. Objective. To determine the CagA phosphorylation motifs pattern (EPIYA pattern) in Cuban H. pylori isola...
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CONTEXT Helicobacter pylori (H. pylori) has a worldwide distribution, but the prevalence of infection, virulence factors, and clinical presentation vary widely according to the studied population. In Brazil, a continental country composed of several ethnicities and cultural habits, the behavior of infection also appears to vary, as many other studies have shown. OBJECTIVES Describe the preval...
متن کاملvacA genotypes in Helicobacter pylori strains isolated from children with and without duodenal ulcer in Brazil.
Data concerning the association between vacA genotypes and disease in children in both developed and developing countries are scarce, especially because of the small number of children with a duodenal ulcer studied. The vacA genotypes of Helicobacter pylori strains obtained from 65 children (24 with a duodenal ulcer and 41 without a duodenal ulcer; 33 girls; mean age, 10.2 years; age range, 1 t...
متن کاملPrevalence of Helicobacter pylori vacA, cagA and iceA genotypes in Nigerian patients with duodenal ulcer disease.
Distinct virulence factors of Helicobacter pylori have been associated with clinical outcome of the infection; however, considerable variations have been reported from different geographic regions. Data on genotypes of African H. pylori isolates are sparse. The aim of this study was to determine the prevalence of specific genotypes of H. pylori in Nigerian patients with duodenal ulcer and non-u...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2005
ISSN: 0031-3998,1530-0447
DOI: 10.1203/01.pdr.0000181380.14230.8b